Omtrent seven-9 % af den kaukasiske befolkning har variationer i CYP2D6 genet som koder for ingen- eller nedsat aktivitet af CYP2D6 (se personlig medicin ). Tramadol et produg der omdannes til den aktive metabolit by using CYP2D6. Patienter med nedsat eller manglende aktivitet af CYP2D6, vil have reduceret- eller manglende effekt af tramadol.Eksper… Read More

"Latest Swedish investigate has proven good leads to scientific trials with highly structured remedy based upon positive reinforcement of preferred behaviours (Kakko, 2011). Within an analysis of a drug-assisted programme for woman prostitutes in Malmö, two achievement components are outlined: efficient liaison with social providers and psychologi… Read More